Chemotherapy Alone vs. Chemotherapy + Surgical Resection in Patients With Limited-metastatic Adenocarcinoma of the Stomach or Esophagogastric Junction

Study ID
NCT02578368

Study type
Interventional

Study phase
Phase 3

Study status
Active, not recruiting

Trial Acronym

FLOT5

Trial Summary

Previously untreated patients with limited metastatic stage (see protocol for details on criteria) will receive 4 cycles of FLOT (5-Fluorouracil, Leucovorin, Oxaliplatin and Docetaxel). Patients without disease progression will be randomized 1:1 to receive additional chemotherapy cycles (4-8 cycles of FLOT) or surgical resection followed by subsequent chemotherapy (4-8 cycles of FLOT). Main objective of the study is overall survival. Most important secondary objective is the quality of life under treatment and during follow-up.

More informations

Trial Starting Date

Feb 29,2016

Requirements

Gender All
Minimum age 18 Years
Maximum age N/A

Enrollement Limit

183