Liver Transplantation in Patients With Unresectable Colorectal Liver Metastases Treated by Chemotherapy

Study ID
NCT02597348

Study type
Interventional

Study phase
Not Applicable

Study status
Active, not recruiting

Trial Acronym

TRANSMET

Trial Summary

This is a multicentric randomized parallel group open trial comparing 5-year survival of chemotherapy followed by LT (Group LT+C) versus chemotherapy alone (Group C) in patients with confirmed unresectable liver-only metastases, well controlled by chemotherapy (no progression) and extensively explored by modern imaging techniques. The primary objective of the trial is to validate in a large multicentric cohort of selected patients the possibility to obtain at least 50% 5-years survival with LT combined to chemotherapy compared to around 10% with chemotherapy alone.

More informations

Trial Starting Date

Feb 29,2016

Requirements

Gender All
Minimum age 18 Years
Maximum age 65 Years

Enrollement Limit