Multicentric Randomised Trial for Resectable Gastric Cancer


NCT02931890

Interventional

Phase 2

Recruiting
CRITICS-II
The CRITICS-II trial aims to identify the optimal preoperative regimen in resectable gastric cancer by comparing three investigational treatment arms: chemotherapy vs. chemotherapy and subsequent chemoradiotherapy vs. chemoradiotherapy. The rationale behind this trial design is based on the following concepts: Preoperative treatment is associated with better patient compliance than postoperative regimens Preoperative treatment increases the likelihood of disease downsizing/downstaging and radical R0 resections Preoperative paclitaxel/carboplatin-based concurrent chemoradiotherapy and DOC chemotherapy are effective, feasible and safe regimens
Dec 21,2017
All
18 Years
N/A
207